Overview of Picked Chemical Compounds and Intermediates

Overview of Picked Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the procedure of various myeloma. Its synthesis or analyze is important for making certain the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound inside the synthesis of imatinib, a drug that targets particular types of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers for example breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their review is very important for optimizing the output approach and making sure substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is applied to deal with breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the therapy of breast most cancers. Many intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug powerful in managing CAS NO. 136572-09-3 cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and little cell lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, that have several purposes, including antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which happen to be Utilized in food stuff, pharmaceutical, and 1-AMINO-3-ADAMANTANOL industrial applications.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication employed to deal with variety 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).